Timea Nagy Simon

timea.simon[at]ubbcluj.ro

Pozitie:

CS III

Timea Nagy Simon

Educatie:

Ph.D. Fizica, Universitatea "Babes-Bolyai", Cluj-Napoca, Romania 2013.

M. Sc. Biofizica si Fizica Medicala, Universitatea "Babes-Bolyai", Cluj-Napoca, Romania 2010.

B. Sc. Fizica Medicala, Universitatea "Babes-Bolyai", Cluj-Napoca, Romania 2008

 

Directii de cercetare:

Nanoparticule hibride fotoactive pentru terapia combinata a cancerului.

 

Aptitudini:

Obtinerea nanoparticulelor de aur prin sinteza chimica; Functionalizarea nanoparticulelor; Masuratori spectroscopice (UV-Vis, Raman, SERS) si imprastiere dinamica a luminii (DLS); Microscopie de fluorescenta si in camp intunecat; Culturi celulare.

Publicatii recente:

  1. T. Nagy Simon, M. Potara, A. M. Craciun, E. Licarete, S. Astilean, IR780-dye loaded gold nanoparticles as new near infrared activatable nanotheranostic agents for simultaneous photodynamic and photothermal therapy and intracellular tracking by surface enhanced resonant Raman scattering imaging, J. Colloid Interface Sci. 517 (2018) 239-250. (doi)
  2. T. Nagy Simon, A. Tatar, A. M. Craciun, A. Vulpoi, M. A. Jurj, A. Florea, C. Tomuleasa, I. Berindan-Neagoe, S. Astilean, S. Boca, Antibody Conjugated, Raman Tagged Hollow Gold–Silver Nanospheres for Specific Targeting and Multimodal Dark-Field/SERS/Two Photon-FLIM Imaging of CD19(+) B Lymphoblasts, ACS Appl. Mater. Interfaces 9 (2017) 21155-68. (doi)
  3. K. Magyari, T. Nagy Simon, A. Vulpoi, R.A. Popescu, E. Licarete, R. Stefan, K. Hernádi, I. Papuc, L. Baia, Novel bioactive glass-AuNP composites for biomedical applications, Mater. Sci. Eng., C 76 (2017) 752-759. (doi)
  4. M. Potara, T. Nagy Simon, A. M. Craciun, S. Suarasan, E. Licarete, F. Imre Lucaci, and S. Astilean, Carboplatin-Loaded, Raman-Encoded, Chitosan-Coated Silver Nanotriangles as Multimodal Traceable Nanotherapeutic Delivery Systems and pH Reporters inside Human Ovarian Cancer Cells, ACS Appl. Mater. Interfaces 9 (2017) 32565–32576. (doi)
  5. S. Boca, C. Lucan, I. Frinc, B. Petrushev, T. Simon, C. Berce et al., Gold Nanoparticles Conjugated with Rituximab for the Treatment of Chronic Lymphocytic Leukemia, FARMACIA 64 (2016) 688-698. (doi)
  6. A. Tatar, T. Nagy Simon, C. Tomuleasa, S. Boca, S. Astilean, Nanomedicine approaches in acute lymphoblastic leukemia, J. Controlled Release 238 (2016) 123-138. (doi)
  7. B. Petrushev, S. Boca, T. Simon, C. Berce, I. Frinc, D. Dima, S. Selicean, G.-A. Gafencu, A. Tanase, M. Zdrenghea, A. Florea, S. Suarasan, L. Dima, R. Stanciu, A. Jurj, A. Buzoianu, A. Cucuianu, S. Astilean, A. Irimie, C. Tomuleasa, I. Berindan-Neagoe, Gold nanoparticles enhance the effect of tyrosin kinase inhibitors in acute myeloid leukemia therapy, Int. J. Nanomedicine 11 (2016) 641-660. (doi)
  8. S. Suarasan, T. Simon, S. Boca, C. Tomuleasa, S. Astilean, Gelatin coated gold nanoparticles as carriers of FLT3 inhibitors for acute myeloid leukemia treatment, Chem Biol Drug Des 87 (2016) 927-935. (doi)
  9. T. Simon, M. Potara, A. M. Gabudean, E. Licarete, M. Banciu, S. Astilean, Designing Theranostic Agents Based on Pluronic Stabilized Gold Nanoaggregates Loaded with Methylene Blue for Multimodal Cell Imaging and Enhanced Photodynamic Therapy, ACS Appl. Mater. Interfaces 7 (2015) 16191-16201. (doi)
  10. T. Simon, C. Tomuleasa, A. Bojan, I. Berindan-Neagoe, S. Boca and S. Astilean, Design of FLT3 Inhibitor - Gold Nanoparticle Conjugates as Potential Therapeutic Agents for the Treatment of Acute Myeloid Leukemia, Nanoscale Res. Lett. 10 (2015) 466. (doi)
  11. M. Potara, M. Bawaskar, T. Simon, S. Gaikwad, E. Licarete, A. Ingle, M. Banciu, A. Vulpoi, S. Astilean, M. Rai, Biosynthesized silver nanoparticles performing as biogenic SERS-nanotags for investigation of C26 colon carcinoma cells, Colloids Surf. B 133 (2015) 296-303. (doi)
  12. S. Boca-Farcau, M. Potara, T. Simon, A. Juhem, P. Baldeck and S. Astilean, Folic Acid-Conjugated, SERS-Labeled Silver Nanotriangles for Multimodal Detection and Targeted Photothermal Treatment on Human Ovarian Cancer Cells, Mol. Pharm. 11 (2014) 391–399. (doi)
  13. C. Tira, D.S. Tira, T. SImon, S. Astilean, Finite-Difference Time-Domain (FDTD) design of gold nanoparticle chains with specific surface plasmon resonance, J. Mol. Struct. 1072 (2014) 137-–143. (doi)
  14. B. Marta, E. Jakab, M. Potara, T. Simon, F. Imre-Lucaci,L. Barbu-Tudoran, O. Popescu, S. Astilean, Pluronic-coated silver nanoprisms: Synthesis, characterization andtheir antibacterial activity, Colloids Surf. A 441 (2014) 77-83. (doi)
  15. M. Iliut, A. M. Gabudean, C. Leordean, T. Simon, C. M. Teodorescu, S. Astilean, Riboflavin enhanced fluorescence of highly reduced graphene oxide, Chem. Phys. Lett. 586 (2013) 127–131. (doi)
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