Simion Astilean



Professor at the Faculty of Physics

Simion Astilean


1990-1993: PhD in Physics, Joseph Fourier University,

Grenoble, France

1994 - 1996: Lecturer, Faculty of Physics,

Babes-Bolyai University, Cluj-Napoca, Romania

1996 – 2002: Associate Professor, Faculty of Physics,

Babes-Bolyai University, Cluj-Napoca, Romania

Since 2002-: Full Professor, Faculty of Physics,

Babes-Bolyai University, Cluj-Napoca, Romania


Research Interests:

Reasearch achievements: - Co-author of 167 scientific ISI articles with over 2040 citations (h-index = 30) and 14 invited conferences; - Co-author of one international book published by Springer Verlag Ed. - Contributor to 2 international books (chapter author). - Co-author to 3 books published in Romanian. - Project leader and partner leader of 8 funded national and 1 international projects. - Supervision of 5 PhD thesis in progress, 13 completed PhD thesis, 2 enrolled in international joint program.



Optical spectroscopy: SERS, confocal Raman microscopy, FT-IR, fluorescence, UV-VIS molecular and plasmonic spectroscopy, dark-field microscopy, ‘hole-burning” optical spectroscopy, etc.

Nanofabrication and characterization: chemical synthesis of noble metal nanoparticles and hybrids nanoparticles, coloidal self-assembly, nanosphere lithography, thin film deposition, spin-coating, plasma cleaning, reactive ion etching; surface activation and functionalization, atomic force and electronic microscopy characterization, etc.

Numerical simulation: rigorous coupled wave analysis (RCWA) and finite-difference time-domain (FDTD).

Latest publications:

  1. M. Potara, M. Focsan, A. M. Craciun, I. Botiz, S. Astilean, Polymer-coated plasmonic nanoparticles for environmental remediation: Synthesis, functionalization, and properties chapter in New Polymer Nanocomposites for Environmental Remediation, Elsevier - (2018) 361–387. (doi)
  2. A. Campu, F. Lerouge, D. Chateau, F. Chaput, P. Baldeck, S. Parola, D. Maniu, A. M. Craciun, A. Vulpoi, S. Astilean, M. Focsan, Gold NanoBipyramids Performing as Highly Sensitive Dual-Modal Optical Immunosensors, Anal. Chem. 90 (2018) 8567-8575. (doi)
  3. S. Suarasan, E. Licarete, S. Astilean, A-M. Craciun, Probing cellular uptake and tracking of differently shaped gelatin-coated gold nanoparticles inside of ovarian cancer cells by two-photon excited photoluminescence analyzed by fluorescence lifetime imaging (FLIM), Colloids and Surfaces B: Biointerfaces 166 (2018) 135-143. (doi)
  4. T. Nagy Simon, M. Potara, A. M. Craciun, E. Licarete, S. Astilean, IR780-dye loaded gold nanoparticles as new near infrared activatable nanotheranostic agents for simultaneous photodynamic and photothermal therapy and intracellular tracking by surface enhanced resonant Raman scattering imaging, J. Colloid Interface Sci. 517 (2018) 239-250. (doi)
  5. A. M. Craciun, M. Focsan, L. Gaina, S. Astilean, Enhanced one- and two-photon excited fluorescence of cationic (phenothiazinyl)vinyl-pyridinium chromophore attached to polyelectrolyte-coated gold nanorods, Dyes Pigm. 136 (2017) 24-30. (doi)
  6. D. Zaharie-Butucel, M. Potara, A.M. Craciun,R. Boukherroub, S. Szunerits, S. Astilean, Revealing the structure and functionality of graphene oxide and reduced graphene oxide/pyrene carboxylic acid interfaces by correlative spectral and imaging analysis, PCCP 19 (2017) 16038-16046. (doi)
  7. C. Tira, I. Ly, R. A.L. Vallee, S. Astilean and C. Farcau, Shaping light spectra and field profiles in metal-coated monolayers of etched microspheres, Optical Materials Express 7 (2017) 2847-2859. (doi)
  8. M. Potara, T. Nagy Simon, A. M. Craciun, S. Suarasan, E. Licarete, F. Imre Lucaci, and S. Astilean, Carboplatin-Loaded, Raman-Encoded, Chitosan-Coated Silver Nanotriangles as Multimodal Traceable Nanotherapeutic Delivery Systems and pH Reporters inside Human Ovarian Cancer Cells, ACS Appl. Mater. Interfaces 9 (2017) 32565–32576. (doi)
  9. I. Botiz, M-A. Codescu, C. Farcau, C. Leordean, S. Astilean, C. Silva, N. Stingelin, Convective self-assembly of pi-conjugated oligomers and polymers, J. Mater. Chem. C 5 (2017) 2513-2518. (doi)
  10. T. Nagy Simon, A. Tatar, A. M. Craciun, A. Vulpoi, M. A. Jurj, A. Florea, C. Tomuleasa, I. Berindan-Neagoe, S. Astilean, S. Boca, Antibody Conjugated, Raman Tagged Hollow Gold–Silver Nanospheres for Specific Targeting and Multimodal Dark-Field/SERS/Two Photon-FLIM Imaging of CD19(+) B Lymphoblasts, ACS Appl. Mater. Interfaces 9 (2017) 21155-68. (doi)
  11. N.Djaker, S. Sultana, D.Issaad, S. Boca, H. Moustaoui, J.Spadavecchia, A. Medjahed, M. Bouafia, S. Astilean, M. Lamy de la Chapelle, Spherical and Flower-Shaped Gold Nanoparticles Characterization by Scattering Correlation Spectroscopy, J. Phys. Chem. C 120 (2016) 11700–11708. (doi)
  12. M. Potara, C. Farcau, I. Botiz, S. Astilean, Detection of Environmental Pollutants by Surface-Enhanced Raman Spectroscopy chapter in Advanced Environmental Analysis: Applications of Nanomaterials, Royal Society of Chemistry - (2016) 477-503. (doi)
  13. S. Suarasan, M. Focsan, M. Potara, O. Soritau, A. Florea, D. Maniu, S. Astilean, Doxorubicin-Incorporated Nanotherapeutic Delivery System Based on Gelatin-Coated Gold Nanoparticles: Formulation, Drug Release, and Multimodal Imaging of Cellular Internalization, ACS Applied materials and interfaces 8 (2016) 22900-22913. (doi)
  14. C. Berce, C. Lucan, B. Petrushev, S. Boca, M. Miclean, O. Sarpataki, S. Astilean, A. Buzoianu, C. Tomuleasa, A. Bojan, In vivo assessment of bone marrow toxicity by gold nanoparticle-based bioconjugates in Crl:CD1(ICR) mice, Int J Nanomedicine 11 (2016) 4261–4273. (doi)
  15. A. Tatar, T. Nagy Simon, C. Tomuleasa, S. Boca, S. Astilean, Nanomedicine approaches in acute lymphoblastic leukemia, J. Controlled Release 238 (2016) 123-138. (doi)

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